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Conditional Disabled-1 Deletion in Mice Alters Hippocampal Neurogenesis and Reduces Seizure Threshold

Many animal models of temporal lobe epilepsy (TLE) exhibit altered neurogenesis arising from progenitors within the dentate gyrus subgranular zone (SGZ). Aberrant integration of new neurons into the existing circuit is thought to contribute to epileptogenesis. In particular, adult-born neurons that...

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Publicado en:Front Neurosci
Autores principales: Korn, Matthew J., Mandle, Quinton J., Parent, Jack M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766299/
https://ncbi.nlm.nih.gov/pubmed/26941603
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2016.00063
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