Taste Masking of Griseofulvin and Caffeine Anhydrous Using Kleptose Linecaps DE17 by Hot Melt Extrusion

The objective of this project was to investigate the potential of Kleptose Linecaps DE17 (KLD) in masking the unpleasant/bitter taste of therapeutic agents by hot melt extrusion (HME). Griseofulvin (GRI) and caffeine anhydrous (CA) were used as a bitter active pharmaceutical ingredient (API) model d...

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Publicat a:AAPS PharmSciTech
Autors principals: Juluri, Abhishek, Popescu, Carmen, Zhou, Leon, Murthy, Reena N., Gowda, Vanaja K., P, Chetan Kumar, Pimparade, Manjeet B., Repka, Michael A., Murthy, S. Narasimha
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766133/
https://ncbi.nlm.nih.gov/pubmed/26288942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-015-0374-1
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