Taste Masking of Griseofulvin and Caffeine Anhydrous Using Kleptose Linecaps DE17 by Hot Melt Extrusion

The objective of this project was to investigate the potential of Kleptose Linecaps DE17 (KLD) in masking the unpleasant/bitter taste of therapeutic agents by hot melt extrusion (HME). Griseofulvin (GRI) and caffeine anhydrous (CA) were used as a bitter active pharmaceutical ingredient (API) model d...

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Detalhes bibliográficos
Publicado no:AAPS PharmSciTech
Main Authors: Juluri, Abhishek, Popescu, Carmen, Zhou, Leon, Murthy, Reena N., Gowda, Vanaja K., P, Chetan Kumar, Pimparade, Manjeet B., Repka, Michael A., Murthy, S. Narasimha
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2015
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766133/
https://ncbi.nlm.nih.gov/pubmed/26288942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-015-0374-1
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