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Development of Tablet Formulation of Amorphous Solid Dispersions Prepared by Hot Melt Extrusion Using Quality by Design Approach

The objective of the study was to identify the extragranular component requirements (level and type of excipients) to develop an immediate release tablet of solid dispersions prepared by hot melt extrusion (HME) process using commonly used HME polymers. Solid dispersions of compound X were prepared...

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Detalhes bibliográficos
Publicado no:AAPS PharmSciTech
Main Authors: Agrawal, Anjali, Dudhedia, Mayur, Deng, Weibin, Shepard, Kevin, Zhong, Li, Povilaitis, Edward, Zimny, Ewa
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766115/
https://ncbi.nlm.nih.gov/pubmed/26757898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-015-0472-0
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