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Development of Tablet Formulation of Amorphous Solid Dispersions Prepared by Hot Melt Extrusion Using Quality by Design Approach

The objective of the study was to identify the extragranular component requirements (level and type of excipients) to develop an immediate release tablet of solid dispersions prepared by hot melt extrusion (HME) process using commonly used HME polymers. Solid dispersions of compound X were prepared...

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Dettagli Bibliografici
Pubblicato in:AAPS PharmSciTech
Autori principali: Agrawal, Anjali, Dudhedia, Mayur, Deng, Weibin, Shepard, Kevin, Zhong, Li, Povilaitis, Edward, Zimny, Ewa
Natura: Artigo
Lingua:Inglês
Pubblicazione: Springer US 2016
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766115/
https://ncbi.nlm.nih.gov/pubmed/26757898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-015-0472-0
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