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Development of Tablet Formulation of Amorphous Solid Dispersions Prepared by Hot Melt Extrusion Using Quality by Design Approach

The objective of the study was to identify the extragranular component requirements (level and type of excipients) to develop an immediate release tablet of solid dispersions prepared by hot melt extrusion (HME) process using commonly used HME polymers. Solid dispersions of compound X were prepared...

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Dades bibliogràfiques
Publicat a:AAPS PharmSciTech
Autors principals: Agrawal, Anjali, Dudhedia, Mayur, Deng, Weibin, Shepard, Kevin, Zhong, Li, Povilaitis, Edward, Zimny, Ewa
Format: Artigo
Idioma:Inglês
Publicat: Springer US 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766115/
https://ncbi.nlm.nih.gov/pubmed/26757898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1208/s12249-015-0472-0
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