Matrix Metalloprotease 3 Exacerbates Hemorrhagic Transformation and Worsens Functional Outcomes in Hyperglycemic Stroke

BACKGROUND AND PURPOSE: Acute hyperglycemia worsens the clinical outcomes and exacerbates cerebral hemorrhage after stroke. The mediators of hemorrhagic transformation (HT) in hyperglycemic stroke are not fully understood. Matrix metalloproteinase 3 (MMP3) plays a critical role in the tissue plasmin...

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Gepubliceerd in:Stroke
Hoofdauteurs: Hafez, Sherif, Abdelsaid, Mohammed, El-Shafey, Sally, Johnson, Maribeth H., Fagan, Susan C., Ergul, Adviye
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2016
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766051/
https://ncbi.nlm.nih.gov/pubmed/26839355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/STROKEAHA.115.011258
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