Vascular protection in diabetic stroke: role of matrix metalloprotease-dependent vascular remodeling

Temporary focal ischemia causes greater hemorrhagic transformation (HT) in diabetic Goto-Kakizaki (GK) rats, a model with increased cerebrovascular matrix metalloprotease (MMP) activity and tortuosity. The objective of the current study was to test the hypotheses that (1) diabetes-induced cerebrovas...

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Autors principals: Elgebaly, Mostafa M, Prakash, Roshini, Li, Weiguo, Ogbi, Safia, Johnson, Maribeth H, Mezzetti, Erin M, Fagan, Susan C, Ergul, Adviye
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group 2010
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3002883/
https://ncbi.nlm.nih.gov/pubmed/20664613
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jcbfm.2010.120
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