The Failing Heart Relies on Ketone Bodies as a Fuel

BACKGROUND: Significant evidence indicates that the failing heart is “energy-starved”. During the development of heart failure, the capacity of the heart to utilize fatty acids, the chief fuel, is diminished. Identification of alternate pathways for myocardial fuel oxidation could unveil novel strat...

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Bibliographic Details
Published in:Circulation
Main Authors: Aubert, Gregory, Martin, Ola J., Horton, Julie L., Lai, Ling, Vega, Rick B., Leone, Teresa C., Koves, Timothy, Gardell, Stephen J., Krüger, Marcus, Hoppel, Charles L., Lewandowski, E. Douglas, Crawford, Peter A., Muoio, Deborah M., Kelly, Daniel P.
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4766035/
https://ncbi.nlm.nih.gov/pubmed/26819376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.115.017355
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