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Modulation of iron metabolism by iron chelation regulates intracellular calcium and increases sensitivity to doxorubicin

Increased intracellular iron levels can both promote cell proliferation and death, as such; iron has a “two-sided effect” in the delicate balance of human health. Though the role of iron in the development of cancer remains unclear, investigations of iron chelators as anti-tumor agents have revealed...

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Bibliografiska uppgifter
I publikationen:Bosn J Basic Med Sci
Huvudupphovsmän: Yalcintepe, Leman, Halis, Emre
Materialtyp: Artigo
Språk:Inglês
Publicerad: Association of Basic Medical Sciences of Federation of Bosnia and Herzegovina 2016
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4765934/
https://ncbi.nlm.nih.gov/pubmed/26773173
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.17305/bjbms.2016.576
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