Dynamic changes of RNA-sequencing expression for precision medicine: N-of-1-pathways Mahalanobis distance within pathways of single subjects predicts breast cancer survival

Motivation: The conventional approach to personalized medicine relies on molecular data analytics across multiple patients. The path to precision medicine lies with molecular data analytics that can discover interpretable single-subject signals (N-of-1). We developed a global framework, N-of-1-pathw...

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Bibliografiske detaljer
Udgivet i:Bioinformatics
Main Authors: Schissler, A. Grant, Gardeux, Vincent, Li, Qike, Achour, Ikbel, Li, Haiquan, Piegorsch, Walter W., Lussier, Yves A.
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2015
Fag:
Ismb/Eccb 2015 Proceedings Papers Committee July 10 to July 14, 2015, Dublin, Ireland
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4765863/
https://ncbi.nlm.nih.gov/pubmed/26072495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bioinformatics/btv253
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