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Metabolic regulation by SIRT3: implications for tumorigenesis

Cancer cells meet their needs for energy and biomass production by consuming high levels of nutrients and rewiring metabolism to support macromolecular biosynthesis. Mitochondrial enzymes play central roles in anabolic growth, and acetylation may provide a key layer of regulation over mitochondrial...

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Bibliografiske detaljer
Udgivet i:Trends Mol Med
Main Authors: Finley, Lydia W. S., Haigis, Marcia C.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4765807/
https://ncbi.nlm.nih.gov/pubmed/22749020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2012.05.004
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