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Metabolic regulation by SIRT3: implications for tumorigenesis

Cancer cells meet their needs for energy and biomass production by consuming high levels of nutrients and rewiring metabolism to support macromolecular biosynthesis. Mitochondrial enzymes play central roles in anabolic growth, and acetylation may provide a key layer of regulation over mitochondrial...

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Detalhes bibliográficos
Publicado no:Trends Mol Med
Main Authors: Finley, Lydia W. S., Haigis, Marcia C.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4765807/
https://ncbi.nlm.nih.gov/pubmed/22749020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmed.2012.05.004
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