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Model-Driven Understanding of Palmitoylation Dynamics: Regulated Acylation of the Endoplasmic Reticulum Chaperone Calnexin

Cellular functions are largely regulated by reversible post-translational modifications of proteins which act as switches. Amongst these, S-palmitoylation is unique in that it confers hydrophobicity. Due to technical difficulties, the understanding of this modification has lagged behind. To investig...

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Dettagli Bibliografici
Pubblicato in:PLoS Comput Biol
Autori principali: Dallavilla, Tiziano, Abrami, Laurence, Sandoz, Patrick A., Savoglidis, Georgios, Hatzimanikatis, Vassily, van der Goot, F. Gisou
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2016
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4765739/
https://ncbi.nlm.nih.gov/pubmed/26900856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004774
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