A Randomized, Double-Blind, Placebo-Controlled Trial of Pleconaril for the Treatment of Neonates With Enterovirus Sepsis

BACKGROUND: Neonatal enterovirus sepsis has high mortality. Antiviral therapy is not available. METHODS: Neonates with suspected enterovirus sepsis (hepatitis, coagulopathy, and/or myocarditis) with onset at ≤15 days of life were randomized 2:1 to receive oral pleconaril or placebo for 7 days. Seria...

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Bibliografische gegevens
Gepubliceerd in:J Pediatric Infect Dis Soc
Hoofdauteurs: Abzug, Mark J., Michaels, Marian G., Wald, Ellen, Jacobs, Richard F., Romero, José R., Sánchez, Pablo J., Wilson, Gregory, Krogstad, Paul, Storch, Gregory A., Lawrence, Robert, Shelton, Mark, Palmer, April, Robinson, Joan, Dennehy, Penelope, Sood, Sunil K., Cloud, Gretchen, Jester, Penelope, Acosta, Edward P., Whitley, Richard, Kimberlin, David
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Oxford University Press 2016
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Original Articles and Commentaries
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4765488/
https://ncbi.nlm.nih.gov/pubmed/26407253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jpids/piv015
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