A Randomized, Double-Blind, Placebo-Controlled Trial of Pleconaril for the Treatment of Neonates With Enterovirus Sepsis

BACKGROUND: Neonatal enterovirus sepsis has high mortality. Antiviral therapy is not available. METHODS: Neonates with suspected enterovirus sepsis (hepatitis, coagulopathy, and/or myocarditis) with onset at ≤15 days of life were randomized 2:1 to receive oral pleconaril or placebo for 7 days. Seria...

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Библиографические подробности
Опубликовано в: :J Pediatric Infect Dis Soc
Главные авторы: Abzug, Mark J., Michaels, Marian G., Wald, Ellen, Jacobs, Richard F., Romero, José R., Sánchez, Pablo J., Wilson, Gregory, Krogstad, Paul, Storch, Gregory A., Lawrence, Robert, Shelton, Mark, Palmer, April, Robinson, Joan, Dennehy, Penelope, Sood, Sunil K., Cloud, Gretchen, Jester, Penelope, Acosta, Edward P., Whitley, Richard, Kimberlin, David
Формат: Artigo
Язык:Inglês
Опубликовано: Oxford University Press 2016
Предметы:
Original Articles and Commentaries
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4765488/
https://ncbi.nlm.nih.gov/pubmed/26407253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jpids/piv015
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