Exosome-mediated transfer of miR-222 is sufficient to increase tumor malignancy in melanoma

BACKGROUND: Growing evidence is showing that metastatic cell populations are able to transfer their characteristics to less malignant cells. Exosomes (EXOs) are membrane vesicles of endocytic origin able to convey their cargo of mRNAs, microRNAs (miRs), proteins and lipids from donors to proximal as...

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Bibliografski detalji
Izdano u:J Transl Med
Glavni autori: Felicetti, Federica, De Feo, Alessandra, Coscia, Carolina, Puglisi, Rossella, Pedini, Francesca, Pasquini, Luca, Bellenghi, Maria, Errico, Maria Cristina, Pagani, Elena, Carè, Alessandra
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2016
Teme:
Research
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4765208/
https://ncbi.nlm.nih.gov/pubmed/26912358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-0811-2
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