Exosome-mediated transfer of miR-222 is sufficient to increase tumor malignancy in melanoma

BACKGROUND: Growing evidence is showing that metastatic cell populations are able to transfer their characteristics to less malignant cells. Exosomes (EXOs) are membrane vesicles of endocytic origin able to convey their cargo of mRNAs, microRNAs (miRs), proteins and lipids from donors to proximal as...

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Dades bibliogràfiques
Publicat a:J Transl Med
Autors principals: Felicetti, Federica, De Feo, Alessandra, Coscia, Carolina, Puglisi, Rossella, Pedini, Francesca, Pasquini, Luca, Bellenghi, Maria, Errico, Maria Cristina, Pagani, Elena, Carè, Alessandra
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2016
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4765208/
https://ncbi.nlm.nih.gov/pubmed/26912358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-016-0811-2
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