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H2A.Z.1 mono-ubiquitylation antagonizes BRD2 to maintain poised chromatin in ESCs
Histone variant H2A.Z occupies the promoters of active and poised, bivalent genes in ESCs to regulate developmental programs, yet how it contributes to these contrasting states is poorly understood. Here, we investigate the function of H2A.Z.1 mono-ubiquitylation (H2A.Z.1ub) by mutation of the PRC1...
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| Publicado no: | Cell Rep |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4764991/ https://ncbi.nlm.nih.gov/pubmed/26804911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2015.12.100 |
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