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Circulating FGF21 proteolytic processing mediated by fibroblast activation protein

Fibroblast growth factor 21 (FGF21), a hormone implicated in the regulation of glucose homoeostasis, insulin sensitivity, lipid metabolism and body weight, is considered to be a promising therapeutic target for the treatment of metabolic disorders. Despite observations that FGF21 is rapidly proteoly...

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Detalhes bibliográficos
Publicado no:Biochem J
Main Authors: Zhen, Eugene Y., Jin, Zhaoyan, Ackermann, Bradley L., Thomas, Melissa K., Gutierrez, Jesus A.
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764976/
https://ncbi.nlm.nih.gov/pubmed/26635356
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20151085
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