Smad2 and Smad3 have differential sensitivity in relaying TGFβ signaling and inversely regulate early lineage specification

The transforming growth factor beta (TGFβ) related signaling is one of the most important signaling pathways regulating early developmental events. Smad2 and Smad3 are structurally similar and it is mostly considered that they are equally important in mediating TGFβ signals. Here, we show that Smad3...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Liu, Ling, Liu, Xu, Ren, Xudong, Tian, Yue, Chen, Zhenyu, Xu, Xiangjie, Du, Yanhua, Jiang, Cizhong, Fang, Yujiang, Liu, Zhongliang, Fan, Beibei, Zhang, Quanbin, Jin, Guohua, Yang, Xiao, Zhang, Xiaoqing
Format: Artigo
Language:Inglês
Published: Nature Publishing Group 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764856/
https://ncbi.nlm.nih.gov/pubmed/26905010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21602
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