Smad2 and Smad3 have differential sensitivity in relaying TGFβ signaling and inversely regulate early lineage specification

The transforming growth factor beta (TGFβ) related signaling is one of the most important signaling pathways regulating early developmental events. Smad2 and Smad3 are structurally similar and it is mostly considered that they are equally important in mediating TGFβ signals. Here, we show that Smad3...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Liu, Ling, Liu, Xu, Ren, Xudong, Tian, Yue, Chen, Zhenyu, Xu, Xiangjie, Du, Yanhua, Jiang, Cizhong, Fang, Yujiang, Liu, Zhongliang, Fan, Beibei, Zhang, Quanbin, Jin, Guohua, Yang, Xiao, Zhang, Xiaoqing
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764856/
https://ncbi.nlm.nih.gov/pubmed/26905010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21602
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