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Tunable protein synthesis by transcript isoforms in human cells

Eukaryotic genes generate multiple RNA transcript isoforms though alternative transcription, splicing, and polyadenylation. However, the relationship between human transcript diversity and protein production is complex as each isoform can be translated differently. We fractionated a polysome profile...

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Publicat a:eLife
Autors principals: Floor, Stephen N, Doudna, Jennifer A
Format: Artigo
Idioma:Inglês
Publicat: eLife Sciences Publications, Ltd 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764583/
https://ncbi.nlm.nih.gov/pubmed/26735365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.10921
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