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Tunable protein synthesis by transcript isoforms in human cells

Eukaryotic genes generate multiple RNA transcript isoforms though alternative transcription, splicing, and polyadenylation. However, the relationship between human transcript diversity and protein production is complex as each isoform can be translated differently. We fractionated a polysome profile...

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Библиографические подробности
Опубликовано в: :eLife
Главные авторы: Floor, Stephen N, Doudna, Jennifer A
Формат: Artigo
Язык:Inglês
Опубликовано: eLife Sciences Publications, Ltd 2016
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764583/
https://ncbi.nlm.nih.gov/pubmed/26735365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.10921
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