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Correction of a Genetic Deficiency in Pantothenate Kinase 1 using Phosphopantothenate Replacement Therapy

Coenzyme A (CoA) is a ubiquitous cofactor involved in numerous essential biochemical transformations, and along with its thioesters is a key regulator of intermediary metabolism. Pantothenate (vitamin B(5)) phosphorylation by pantothenate kinase (PanK) is thought to control the rate of CoA productio...

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Detalhes bibliográficos
Publicado no:Mol Genet Metab
Main Authors: Zano, Stephen P., Pate, Caroline, Frank, Matthew, Rock, Charles, Jackowski, Suzanne
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764103/
https://ncbi.nlm.nih.gov/pubmed/26549575
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2015.10.011
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