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Gonadotropin and kisspeptin gene expression, but not GnRH, are impaired in cFOS deficient mice
cFOS is a pleiotropic transcription factor, which binds to the AP1 site in the promoter of target genes. In the pituitary gonadotropes, cFOS mediates induction of FSHβ and GnRH receptor genes. Herein, we analyzed reproductive function in the cFOS-deficient mice to determine its role in vivo. In the...
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| Publicat a: | Mol Cell Endocrinol |
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| Autors principals: | , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2015
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4764054/ https://ncbi.nlm.nih.gov/pubmed/25958044 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2015.04.033 |
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