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Gonadotropin and kisspeptin gene expression, but not GnRH, are impaired in cFOS deficient mice

cFOS is a pleiotropic transcription factor, which binds to the AP1 site in the promoter of target genes. In the pituitary gonadotropes, cFOS mediates induction of FSHβ and GnRH receptor genes. Herein, we analyzed reproductive function in the cFOS-deficient mice to determine its role in vivo. In the...

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Bibliografski detalji
Izdano u:Mol Cell Endocrinol
Glavni autori: Xie, Changchuan, Jonak, Carrie R., Kauffman, Alexander S., Coss, Djurdjica
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4764054/
https://ncbi.nlm.nih.gov/pubmed/25958044
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mce.2015.04.033
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