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Kisspeptin Can Stimulate Gonadotropin-Releasing Hormone (GnRH) Release by a Direct Action at GnRH Nerve Terminals

The G protein-coupled receptor GPR54, and its peptide ligand kisspeptin (Kp), are crucial for the induction and maintenance of mammalian reproductive function. GPR54 is expressed by GnRH neurons and is directly activated by Kp to stimulate GnRH release. We hypothesized that Kp may be able to act at...

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Main Authors: d'Anglemont de Tassigny, Xavier, Fagg, Lisa A., Carlton, Mark B. L., Colledge, William H.
格式: Artigo
語言:Inglês
出版: The Endocrine Society 2008
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2488229/
https://ncbi.nlm.nih.gov/pubmed/18450966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2007-1487
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