Neutrophil elastase promotes myofibroblast differentiation in lung fibrosis

IPF is a progressive lung disorder characterized by fibroblast proliferation and myofibroblast differentiation. Although neutrophil accumulation within IPF lungs has been negatively correlated with outcomes, the role played by neutrophils in lung fibrosis remains poorly understood. We have demonstra...

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Dades bibliogràfiques
Publicat a:J Leukoc Biol
Autors principals: Gregory, Alyssa D., Kliment, Corrine R., Metz, Heather E., Kim, Kyoung-Hee, Kargl, Julia, Agostini, Brittani A., Crum, Lauren T., Oczypok, Elizabeth A., Oury, Tim A., Houghton, A. McGarry
Format: Artigo
Idioma:Inglês
Publicat: Society for Leukocyte Biology 2015
Matèries:
Spotlight on Leading Edge Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4763951/
https://ncbi.nlm.nih.gov/pubmed/25743626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3HI1014-493R
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