Neutrophil elastase promotes myofibroblast differentiation in lung fibrosis

IPF is a progressive lung disorder characterized by fibroblast proliferation and myofibroblast differentiation. Although neutrophil accumulation within IPF lungs has been negatively correlated with outcomes, the role played by neutrophils in lung fibrosis remains poorly understood. We have demonstra...

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Detaylı Bibliyografya
Yayımlandı:J Leukoc Biol
Asıl Yazarlar: Gregory, Alyssa D., Kliment, Corrine R., Metz, Heather E., Kim, Kyoung-Hee, Kargl, Julia, Agostini, Brittani A., Crum, Lauren T., Oczypok, Elizabeth A., Oury, Tim A., Houghton, A. McGarry
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Society for Leukocyte Biology 2015
Konular:
Spotlight on Leading Edge Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4763951/
https://ncbi.nlm.nih.gov/pubmed/25743626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1189/jlb.3HI1014-493R
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