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Neutrophil Elastase-Mediated Degradation of IRS-1 Accelerates Lung Tumor Growth
Lung cancer is the leading cause of cancer death worldwide1. Recent data suggest that tumor-associated inflammatory cells may modify lung tumor growth and invasiveness2-3. To determine the role of neutrophil elastase (NE or Elane) on tumor progression, we utilized the LSL-K-ras model of murine lung...
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| Main Authors: | , , , , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2821801/ https://ncbi.nlm.nih.gov/pubmed/20081861 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nm.2084 |
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