N-Acylethanolamine-hydrolyzing acid amidase inhibition increases colon N-palmitoylethanolamine levels and counteracts murine colitis

N-Palmitoylethanolamine or palmitoylethanolamide (PEA) is an anti-inflammatory compound that was recently shown to exert peroxisome proliferator-activated receptor-α-dependent beneficial effects on colon inflammation. The actions of PEA are terminated following hydrolysis by 2 enzymes: fatty acid am...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Alhouayek, Mireille, Bottemanne, Pauline, Subramanian, Kumar V., Lambert, Didier M., Makriyannis, Alexandros, Cani, Patrice D., Muccioli, Giulio G.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2015
Assuntos:
Research Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4763939/
https://ncbi.nlm.nih.gov/pubmed/25384424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-255208
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