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Comparative Analysis of the Effects of Neurotrophic Factors CDNF and GDNF in a Nonhuman Primate Model of Parkinson’s Disease

Cerebral dopamine neurotrophic factor (CDNF) belongs to a newly discovered family of evolutionarily conserved neurotrophic factors. We demonstrate for the first time a therapeutic effect of CDNF in a unilateral 6-hydroxydopamine (6-OHDA) lesion model of Parkinson’s disease in marmoset monkeys. Furth...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Garea-Rodríguez, Enrique, Eesmaa, Ave, Lindholm, Päivi, Schlumbohm, Christina, König, Jessica, Meller, Birgit, Krieglstein, Kerstin, Helms, Gunther, Saarma, Mart, Fuchs, Eberhard
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4763937/
https://ncbi.nlm.nih.gov/pubmed/26901822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0149776
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