Systems biology of immunity to MF59-adjuvanted versus nonadjuvanted trivalent seasonal influenza vaccines in early childhood

The dynamics and molecular mechanisms underlying vaccine immunity in early childhood remain poorly understood. Here we applied systems approaches to investigate the innate and adaptive responses to trivalent inactivated influenza vaccine (TIV) and MF59-adjuvanted TIV (ATIV) in 90 14- to 24-mo-old he...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Nakaya, Helder I., Clutterbuck, Elizabeth, Kazmin, Dmitri, Wang, Lili, Cortese, Mario, Bosinger, Steven E., Patel, Nirav B., Zak, Daniel E., Aderem, Alan, Dong, Tao, Del Giudice, Giuseppe, Rappuoli, Rino, Cerundolo, Vincenzo, Pollard, Andrew J., Pulendran, Bali, Siegrist, Claire-Anne
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2016
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4763735/
https://ncbi.nlm.nih.gov/pubmed/26755593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1519690113
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