Systems biology of immunity to MF59-adjuvanted versus nonadjuvanted trivalent seasonal influenza vaccines in early childhood

The dynamics and molecular mechanisms underlying vaccine immunity in early childhood remain poorly understood. Here we applied systems approaches to investigate the innate and adaptive responses to trivalent inactivated influenza vaccine (TIV) and MF59-adjuvanted TIV (ATIV) in 90 14- to 24-mo-old he...

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Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Proc Natl Acad Sci U S A
Päätekijät: Nakaya, Helder I., Clutterbuck, Elizabeth, Kazmin, Dmitri, Wang, Lili, Cortese, Mario, Bosinger, Steven E., Patel, Nirav B., Zak, Daniel E., Aderem, Alan, Dong, Tao, Del Giudice, Giuseppe, Rappuoli, Rino, Cerundolo, Vincenzo, Pollard, Andrew J., Pulendran, Bali, Siegrist, Claire-Anne
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: National Academy of Sciences 2016
Aiheet:
Biological Sciences
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4763735/
https://ncbi.nlm.nih.gov/pubmed/26755593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1519690113
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