Systems biology of immunity to MF59-adjuvanted versus nonadjuvanted trivalent seasonal influenza vaccines in early childhood

The dynamics and molecular mechanisms underlying vaccine immunity in early childhood remain poorly understood. Here we applied systems approaches to investigate the innate and adaptive responses to trivalent inactivated influenza vaccine (TIV) and MF59-adjuvanted TIV (ATIV) in 90 14- to 24-mo-old he...

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書誌詳細
出版年:Proc Natl Acad Sci U S A
主要な著者: Nakaya, Helder I., Clutterbuck, Elizabeth, Kazmin, Dmitri, Wang, Lili, Cortese, Mario, Bosinger, Steven E., Patel, Nirav B., Zak, Daniel E., Aderem, Alan, Dong, Tao, Del Giudice, Giuseppe, Rappuoli, Rino, Cerundolo, Vincenzo, Pollard, Andrew J., Pulendran, Bali, Siegrist, Claire-Anne
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2016
主題:
Biological Sciences
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4763735/
https://ncbi.nlm.nih.gov/pubmed/26755593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1519690113
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