Narcolepsy-Associated HLA Class I Alleles Implicate Cell-Mediated Cytotoxicity

STUDY OBJECTIVES: Narcolepsy with cataplexy is tightly associated with the HLA class II allele DQB1*06:02. Evidence indicates a complex contribution of HLA class II genes to narcolepsy susceptibility with a recent independent association with HLA-DPB1. The cause of narcolepsy is supposed be an autoi...

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Detalhes bibliográficos
Publicado no:Sleep
Main Authors: Tafti, Mehdi, Lammers, Gert J., Dauvilliers, Yves, Overeem, Sebastiaan, Mayer, Geert, Nowak, Jacek, Pfister, Corinne, Dubois, Valérie, Eliaou, Jean-François, Eberhard, Hans-Peter, Liblau, Roland, Wierzbicka, Aleksandra, Geisler, Peter, Bassetti, Claudio L., Mathis, Johannes, Lecendreux, Michel, Khatami, Ramin, Heinzer, Raphaël, Haba-Rubio, José, Feketeova, Eva, Baumann, Christian R., Kutalik, Zoltán, Tiercy, Jean-Marie
Formato: Artigo
Idioma:Inglês
Publicado em: Associated Professional Sleep Societies, LLC 2016
Assuntos:
Neurological Disorders
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4763366/
https://ncbi.nlm.nih.gov/pubmed/26518595
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5665/sleep.5532
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