DQB1 Locus Alone Explains Most of the Risk and Protection in Narcolepsy with Cataplexy in Europe

STUDY OBJECTIVE: Prior research has identified five common genetic variants associated with narcolepsy with cataplexy in Caucasian patients. To replicate and/or extend these findings, we have tested HLA-DQB1, the previously identified 5 variants, and 10 other potential variants in a large European s...

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Detalhes bibliográficos
Main Authors: Tafti, Mehdi, Hor, Hyun, Dauvilliers, Yves, Lammers, Gert J., Overeem, Sebastiaan, Mayer, Geert, Javidi, Sirous, Iranzo, Alex, Santamaria, Joan, Peraita-Adrados, Rosa, Vicario, José L., Arnulf, Isabelle, Plazzi, Giuseppe, Bayard, Sophie, Poli, Francesca, Pizza, Fabio, Geisler, Peter, Wierzbicka, Aleksandra, Bassetti, Claudio L., Mathis, Johannes, Lecendreux, Michel, Donjacour, Claire E.H.M., van der Heide, Astrid, Heinzer, Raphaël, Haba-Rubio, José, Feketeova, Eva, Högl, Birgit, Frauscher, Birgit, Benetó, Antonio, Khatami, Ramin, Cañellas, Francesca, Pfister, Corinne, Scholz, Sabine, Billiard, Michel, Baumann, Christian R., Ercilla, Guadalupe, Verduijn, Willem, Claas, Frans H.J., Dubois, Valérie, Nowak, Jacek, Eberhard, Hans-Peter, Pradervand, Sylvain, Hor, Charlotte N., Testi, Manuela, Tiercy, Jean-Marie, Kutalik, Zoltán
Formato: Artigo
Idioma:Inglês
Publicado em: Associated Professional Sleep Societies, LLC 2014
Assuntos:
DQB1 Locus and the Risk and Protection in Narcolepsy with Cataplexy
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3865351/
https://ncbi.nlm.nih.gov/pubmed/24381371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.5665/sleep.3300
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