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Narcolepsy: immunological aspects

Narcolepsy with cataplexy is a debilitating sleep disorder with an estimated prevalence of about 0.05%. Narcolepsy is caused by a selective loss of hypocretin (orexin) producing neurons in the perifornical hypothalamus. Based on the very strong association with the HLA subtype DQB1*0602, it is curre...

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Detalhes bibliográficos
Main Authors: Overeem, Sebastiaan, Black, John Logan, Lammers, Gert Jan
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2366136/
https://ncbi.nlm.nih.gov/pubmed/18291691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.smrv.2007.07.010
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