Diversity between mammalian tolloid proteinases: Oligomerisation and non-catalytic domains influence activity and specificity

The mammalian tolloid family of metalloproteinases is essential for tissue patterning and extracellular matrix assembly. The four members of the family: bone morphogenetic protein-1 (BMP-1), mammalian tolloid (mTLD), tolloid-like (TLL)-1 and TLL-2 differ in their substrate specificity and activity l...

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Vydáno v:Sci Rep
Hlavní autoři: Bayley, Christopher P., Ruiz Nivia, Hilda D., Dajani, Rana, Jowitt, Thomas A., Collins, Richard F., Rada, Heather, Bird, Louise E., Baldock, Clair
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4763255/
https://ncbi.nlm.nih.gov/pubmed/26902455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep21456
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