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Role of dimerization and substrate exclusion in the regulation of bone morphogenetic protein-1 and mammalian tolloid
The bone morphogenetic protein (BMP)-1/tolloid metalloproteinases are evolutionarily conserved enzymes that are fundamental to dorsal–ventral patterning and tissue morphogenesis. The lack of knowledge regarding how these proteinases recognize and cleave their substrates represents a major hurdle to...
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Main Authors: | , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
National Academy of Sciences
2009
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2689009/ https://ncbi.nlm.nih.gov/pubmed/19429706 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812178106 |
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