Role of dimerization and substrate exclusion in the regulation of bone morphogenetic protein-1 and mammalian tolloid

The bone morphogenetic protein (BMP)-1/tolloid metalloproteinases are evolutionarily conserved enzymes that are fundamental to dorsal–ventral patterning and tissue morphogenesis. The lack of knowledge regarding how these proteinases recognize and cleave their substrates represents a major hurdle to...

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Main Authors: Berry, Richard, Jowitt, Thomas A., Ferrand, Johanna, Roessle, Manfred, Grossmann, J. Günter, Canty-Laird, Elizabeth G., Kammerer, Richard A., Kadler, Karl E., Baldock, Clair
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2009
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2689009/
https://ncbi.nlm.nih.gov/pubmed/19429706
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0812178106
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