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Hypoxia-Regulated Activity of PKCε in the Lens

PURPOSE: To show that hypoxia is necessary to prevent opacification of the lens. Protein kinase C (PKC)-ε serves a role that is distinct from PKC-γ when both PKC isoforms are expressed in the lens. PKCε serves a very important role in hypoxic conditions, helping to prevent opacification of the lens....

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Détails bibliographiques
Publié dans:Invest Ophthalmol Vis Sci
Auteurs principaux: Akoyev, Vladimir, Das, Satyabrata, Jena, Snehalata, Grauer, Laura, Takemoto, Dolores J.
Format: Artigo
Langue:Inglês
Publié: 2008
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4762488/
https://ncbi.nlm.nih.gov/pubmed/18997087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.08-2599
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