In trans T cell tolerance exacerbates experimental allergic encephalomyelitis by interfering with protective antibody responses

F(1) (SJL/J x C57BL/6) mice with MOG35–55-induced EAE recover from disease when treated with Ig-MOG carrying MOG35–55 peptide. However, Ig-PLP1, carrying PLP139–151, induced reduction of anti-MOG antibodies and exacerbated EAE. Herein, we show that Ig-PLP1 specifically reduces the frequency of B cel...

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Detalhes bibliográficos
Publicado no:J Neuroimmunol
Main Authors: Cascio, Jason A., Khairallah, Marie-Therese, Wan, Xiaoxiao, Chen, Weirong, Rowland, Linda M., Dhakal, Mermagya, Miller, Mindy M., Zaghouani, Habib
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4762480/
https://ncbi.nlm.nih.gov/pubmed/24196276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jneuroim.2013.09.022
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