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Developmental Expression of IL-12Rβ2 on Murine Naïve Neonatal T Cells Counters the Up-Regulation of IL-13Rα1 on Primary Th1 Cells and Balances Immunity in the Newborn
Upon exposure to Ag on the day of birth, neonatal mice mount balanced primary Th1 and Th2 responses with the former displaying up-regulated IL-13 receptor alpha 1 (IL-13Rα1) expression. This chain associates with IL-4Rα to form a heteroreceptor (IL-4Rα/IL-13Rα1) that marks the Th1 cells for death by...
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| Hauptverfasser: | , , , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2013
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3679234/ https://ncbi.nlm.nih.gov/pubmed/23650613 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1202207 |
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