Mechanisms Underlying Antigen-Specific Tolerance of Stable and Convertible Th17 Cells During Suppression of Autoimmune Diabetes

Type 1 diabetes involves both T helper (Th)1 and Th17 cells. While the mechanisms underlying the control of Th1 cells are relatively well defined, those operating modulation of Th17 cells remain unknown. Moreover, given that Th17 cells are plastic and can drive disease as stable or convertible T cel...

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Bibliographic Details
Main Authors: Wan, Xiaoxiao, Guloglu, F. Betul, VanMorlan, Amie M., Rowland, Linda M., Jain, Renu, Haymaker, Cara L., Cascio, Jason A., Dhakal, Mermagya, Hoeman, Christine M., Tartar, Danielle M., Zaghouani, Habib
Format: Artigo
Language:Inglês
Published: American Diabetes Association 2012
Subjects:
Immunology and Transplantation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3402331/
https://ncbi.nlm.nih.gov/pubmed/22751698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db11-1723
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