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FoxP3(+)RORγt(+) T helper intermediates display suppressive function against autoimmune diabetes

Recently, traces of double-positive FoxP3(+)RORγt(+) T cells were identified and viewed as dual programming differentiation intermediates geared towards development into T regulatory (Tregs) or Th17 cells. Herein, we report that FoxP3(+)RORγt(+) intermediates arise in the NOD mouse T cell repertoire...

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Autors principals: Tartar, Danielle M., VanMorlan, Amie M., Wan, Xiaoxiao, Guloglu, F. Betul, Jain, Renu, Haymaker, Cara L., Ellis, Jason S., Hoeman, Christine M., Cascio, Jason A., Dhakal, Mermagya, Oukka, Mohamed, Zaghouani, Habib
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843758/
https://ncbi.nlm.nih.gov/pubmed/20181889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903324
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