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FoxP3(+)RORγt(+) T helper intermediates display suppressive function against autoimmune diabetes

Recently, traces of double-positive FoxP3(+)RORγt(+) T cells were identified and viewed as dual programming differentiation intermediates geared towards development into T regulatory (Tregs) or Th17 cells. Herein, we report that FoxP3(+)RORγt(+) intermediates arise in the NOD mouse T cell repertoire...

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Detalhes bibliográficos
Main Authors: Tartar, Danielle M., VanMorlan, Amie M., Wan, Xiaoxiao, Guloglu, F. Betul, Jain, Renu, Haymaker, Cara L., Ellis, Jason S., Hoeman, Christine M., Cascio, Jason A., Dhakal, Mermagya, Oukka, Mohamed, Zaghouani, Habib
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843758/
https://ncbi.nlm.nih.gov/pubmed/20181889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903324
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