FoxP3(+)RORγt(+) T helper intermediates display suppressive function against autoimmune diabetes

Recently, traces of double-positive FoxP3(+)RORγt(+) T cells were identified and viewed as dual programming differentiation intermediates geared towards development into T regulatory (Tregs) or Th17 cells. Herein, we report that FoxP3(+)RORγt(+) intermediates arise in the NOD mouse T cell repertoire...

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Hauptverfasser: Tartar, Danielle M., VanMorlan, Amie M., Wan, Xiaoxiao, Guloglu, F. Betul, Jain, Renu, Haymaker, Cara L., Ellis, Jason S., Hoeman, Christine M., Cascio, Jason A., Dhakal, Mermagya, Oukka, Mohamed, Zaghouani, Habib
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2843758/
https://ncbi.nlm.nih.gov/pubmed/20181889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0903324
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