A MED13-dependent skeletal muscle gene program controls systemic glucose homeostasis and hepatic metabolism

The Mediator complex governs gene expression by linking upstream signaling pathways with the basal transcriptional machinery. However, how individual Mediator subunits may function in different tissues remains to be investigated. Through skeletal muscle-specific deletion of the Mediator subunit MED1...

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Библиографические подробности
Опубликовано в: :Genes Dev
Главные авторы: Amoasii, Leonela, Holland, William, Sanchez-Ortiz, Efrain, Baskin, Kedryn K., Pearson, Mackenzie, Burgess, Shawn C., Nelson, Benjamin R., Bassel-Duby, Rhonda, Olson, Eric N.
Формат: Artigo
Язык:Inglês
Опубликовано: Cold Spring Harbor Laboratory Press 2016
Предметы:
Research Paper
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4762428/
https://ncbi.nlm.nih.gov/pubmed/26883362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.273128.115
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