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On the Role of Internal Water on Protein Thermal Stability: the Case of Homologous G-domains

In this work we address the question whether the enhanced stability of thermophilic proteins has a direct connection with internal hydration. Our model systems are two homologues G-domains of different stability: the mesophilic G domain of the Elongation-Factor thermal unstable protein from E. coli...

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Detalhes bibliográficos
Publicado no:J Phys Chem B
Main Authors: Rahaman, Obaidur, Kalimeri, Maria, Melchionna, Simone, Hénin, Jérôme, Sterpone, Fabio
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4762204/
https://ncbi.nlm.nih.gov/pubmed/25317828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp507571u
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