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Are coarse-grained models apt to detect protein thermal stability? The case of OPEP force field
We present the first investigation of the kinetic and thermodynamic stability of two homologous thermophilic and mesophilic proteins based on the coarse-grained model OPEP. The object of our investigation is a pair of G-domains of relatively large size, 200 amino acids each, with an experimental sta...
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| Vydáno v: | J Non Cryst Solids |
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| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2014
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5238951/ https://ncbi.nlm.nih.gov/pubmed/28100926 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jnoncrysol.2014.07.005 |
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