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Are coarse-grained models apt to detect protein thermal stability? The case of OPEP force field

We present the first investigation of the kinetic and thermodynamic stability of two homologous thermophilic and mesophilic proteins based on the coarse-grained model OPEP. The object of our investigation is a pair of G-domains of relatively large size, 200 amino acids each, with an experimental sta...

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Dettagli Bibliografici
Pubblicato in:J Non Cryst Solids
Autori principali: Kalimeri, Maria, Derreumaux, Philippe, Sterpone, Fabio
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5238951/
https://ncbi.nlm.nih.gov/pubmed/28100926
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jnoncrysol.2014.07.005
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