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CryoEM structure of the yeast U4/U6.U5 tri-snRNP at 3.7 Å resolution
U4/U6.U5 tri-snRNP represents a substantial part of the spliceosome before activation. A cryoEM structure of Saccharomyces cerevisiae U4/U6.U5 tri-snRNP at 3.7Å resolution led to an essentially complete atomic model comprising 30 proteins plus U4/U6 and U5 snRNAs. The structure reveals striking inte...
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| Publicat a: | Nature |
|---|---|
| Autors principals: | , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2016
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4762201/ https://ncbi.nlm.nih.gov/pubmed/26829225 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature16940 |
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