PAX6 Isoforms, along with Reprogramming Factors, Differentially Regulate the Induction of Cornea-specific Genes

PAX6 is the key transcription factor involved in eye development in humans, but the differential functions of the two PAX6 isoforms, isoform-a and isoform-b, are largely unknown. To reveal their function in the corneal epithelium, PAX6 isoforms, along with reprogramming factors, were transduced into...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Sasamoto, Yuzuru, Hayashi, Ryuhei, Park, Sung-Joon, Saito-Adachi, Mihoko, Suzuki, Yutaka, Kawasaki, Satoshi, Quantock, Andrew J., Nakai, Kenta, Tsujikawa, Motokazu, Nishida, Kohji
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4761963/
https://ncbi.nlm.nih.gov/pubmed/26899008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep20807
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